Analysis on Medication Laws of TCM in Treatment of Remission Period of Asthma in Children Based on Literature Click Copy

Analysis on Medication Laws of TCM in Treatment of Remission Period of Asthma in Children Based on Literature

《中国中医药信息杂志》[ISSN:1005-5304/CN:11-3519/R] Volume: 27卷 Issue: 2020年12期 Page: 91-95 Research Field: 中医药信息学 Publishing date: 2020-12-01
Title:
Analysis on Medication Laws of TCM in Treatment of Remission Period of Asthma in Children Based on Literature
Author(s):
WU Di1;  YANG Qinjun1;  LI Zegeng1; 2; 3;  ZHANG Xingxing2; 3;  TONG Jiabing2; 3;  GAO Yating1;  ZHANG Lu1
1. Anhui University of Chinese Medicine, Hefei 230038, China; 2. Institute of Respiratory Disease Prevention and Treatment of Traditional Chinese Medicine, Anhui Academy of Chinese Medicine, Hefei 230031, China; 3. First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China
Keywords:
childhood asthma;  remission period;  TCM;  data mining;  medication laws
PACS:
R2-05；R272.956.225
DOI:
10.19879/j.cnki.1005-5304.201906388
Abstract:
Objective To explore the medication and prescription laws of TCM in the remission period of childhood asthma. Methods Literature about remission period of childhood asthma was retrieved from CNKI, Wanfang Data , VIP and CBM from 1988 to 2018. Literature was screened and entered into the database. Excel 2010 and SPSS 22.0 software were used to conduct frequency statistics, system clustering analysis and factor analysis. Results Totally 216 articles were included, involving 193 kinds of Chinese materia medica. The total frequency of medicine was 2142. The most frequently used medicines were Astragali Radix, Poria, Astractylodis Macrocephalae Rhizoma, Glycyrrhizae Radix et Rhizoma, and Citri Reticulatae Pericarpium. The commonly used medicines were tonifying deficiency medicine, medicine for relieving exterior syndromes, antiphlegm medicine, antitussive and antiasthmatic medicine, and diuresis medicine, belonging to lung, spleen and kidney meridians. The tastes were sweet, bitter, spicy, and the properties were warm, neutral, and cold. Cluster analysis dug out 5 core groups: modified combinations of Astragali Radix, Astractylodis Macrocephalae Rhizoma, Saposhnikoviae Radix, Pinelliae Rhizoma, and Poria. Factor analysis revealed a total of 15 common factors, with a cumulative contribution rate of 67.343%. Conclusion In the remission period of asthma in children, TCM mainly supports the healthy energy, invigorating lung, spleen and kidney. To invigorate lung, spleen and kidney should be combined with drugs for promoting qi, resolving phlegm, promoting blood circulation, and restraining the lung.

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Memo

基金项目：国家重大疑难疾病临床防治中心-中医药重大疑难疾病能力建设项目（支气管哮喘）（2014年）；国家自然科学基金（81874431）；国家中医药管理局内科气虚病证重点研究室（2009年）；安徽省教育厅中医药防治肺系重大疾病重点实验室（2019年）