Systematic Evaluation on Clinical Efficacy and Safety of Qizheng Xiaotong Plaster for Treatment of Knee Osteoarthritis Click Copy

Systematic Evaluation on Clinical Efficacy and Safety of Qizheng Xiaotong Plaster for Treatment of Knee Osteoarthritis

《中国中医药信息杂志》[ISSN:1005-5304/CN:11-3519/R] Volume: 27卷 Issue: 2020年12期 Page: 102-107 Research Field: 中医药信息学 Publishing date: 2020-12-01
Title:
Systematic Evaluation on Clinical Efficacy and Safety of Qizheng Xiaotong Plaster for Treatment of Knee Osteoarthritis
Author(s):
BAI Xue1;  WEN Jianmin2;  YANG Sihong1;  GUAN Yingjie1;  FANG Sainan1;  CHEN Wei1
1. Centre for Evidence-based Chinese Medicine, Beijing University of Chinese Medicine, Beijing 100029, China; 2. Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China
Keywords:
knee osteoarthritis ;  Qizheng Xiaotong Plaster ;  randomized controlled trials ;  systematic evaluation
PACS:
R2-05；R274.94
DOI:
10.19879/j.cnki.1005-5304.201910200
Abstract:
Objective To systematically evaluate the clinical efficacy and safety of Qizheng Xiaotong Plaster in the treatment of knee osteoarthritis. Methods CNKI, Wanfang Data, VIP, CBM, PubMed, and Cochrane Library were systematically retrieved. The search date ended in September 2019. The randomized controlled trials of comparison of Qizheng Xiaotong Plaster and conventional Western treatment for knee osteoarthritis were included. Cochrane Collaboration Network’s bias risk assessment tool was used for methodological quality evaluation of included trials. Meta-analysis was performed using RevMan 5.3 software. Results A total of 12 articles were included, and 1197 patients were enrolled. Most of the included studies did not specifically describe the random grouping method, and did not mention the allocation concealment method, which indicates that there may be selection bias . Meta-analysis results showed that Qizheng Xiaotong Plaster can reduce the VAS score of patients with knee osteoarthritis (MD＝-1.84, 95%CI [-2.42, -1.26]). The results showed that Qizheng Xiaotong Plaster may have advantages in restoring knee joint function, improving joint pain, swelling, tenderness and other symptoms. Conclusion Compared with conventional Western treatment, Qizheng Xiaotong Plaster may have advantages in the treatment of knee osteoarthritis. The conclusion needs to be confirmed by more high-quality, multi-center, large-scale randomized controlled trials.

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Memo

基金项目：中华中医药学会专家共识项目（GS/CACM 201-2019）