[1]叶祖光,李思迪.青蒿素类抗疟药作用机理研究述评[J].中国中医药信息杂志,2014,21(9):5-9.[doi:10.3969/j.issn.1005-5304.2014.09.002]
 YE Zu-guang,LI Si-di.Research Review on Mechanisms of Antimalarial Action of Artemisinin and Its Derivatives[J].zhongguo zhongyiyao xinxi zazhi,2014,21(9):5-9.[doi:10.3969/j.issn.1005-5304.2014.09.002]
点击复制

青蒿素类抗疟药作用机理研究述评

参考文献/References:

[1] 中医研究院中药所药理研究室.青蒿的药理研究[J].新医药学杂志, 1979,8(1):23-32.

[2] Trager W, Jensen JB. Human malaria parasites in continuous culture[J]. Science,1976,193(4254):673-675.

[3] Jensen JB, Trager W. Plasmodium falciparum in culture:Use of outdated erythrocytes and description of the candle jar method[J]. Journal of Parasitology,1977,63(5):883-886.

[4] 叶祖光,李泽琳,傅湘琦,等.体外培养的恶性疟原虫的超微结构[J].微生物学报,1983,23(2):175-178.

[5] 叶祖光,李泽琳,傅湘琦,等.青蒿素和氯喹对体外培养的红内期恶性疟原虫超微结构的影响[J].中医杂志,1982,28(4):65-67.

[6] Ye ZG, Li ZL, Li GQ, et al. Effects of Qinghaosu and chloroquine on the ultrastructure of the erythrocytic stage of P. falciparum in continuous cultivation in vitro[J]. Journal of Traditional Chinese Medicine,1983,3(2):95-102.

[7] Jing JB, Jacobs G, Liang DS, et al. Qinghaosu-induced changes in the morphology of Plasmodium inui[J]. The American Journal of Tropical Medicine and Hygiene,1985,34(3):424-428.

[8] Maeno Y, Toyoshima T, Fujioka H, et al. Morphologic effects of artemisinin in Plasmodium falciparum[J]. The American Journal of Tropical Medicine and Hygiene,1993,49(4):485-491.

[9] 张奎汉,李泽琳.3H-青蒿素在体外培养人恶性疟原虫内的浓集作用[J].中药新药与临床药理,1992,3(4):19-21.

[10] 陈乐义,胡明,张起麟.蒿甲醚对小鼠体内伯氏疟原虫超徽结构的影响[J].中国寄生虫学与寄生虫病杂志,1988(S1):18-19.

[11] 叶祖光,李泽琳,李桂琴,等.青蒿素对感染伯氏疟原虫红细胞及游离疟原虫表面结构的影响[J].寄生虫学与寄生虫病杂志,1986,4(4):260- 261.

[12] Zhao Y, Hall IH, Oswald CB, et al. Antimalarial agents.Ⅲ. Mechanism of action of artesunate against Plasmodium berghei infection[J]. Chemical and Pharmaceutical Bulletin,1987,35(5):2052-2061.

[13] Zhao Y, Hanton WK, Lee KH. Antimalarial agents, 2. Artesunate, an inhibitor of cytochrome oxidase activity in Plasmodium berghei[J]. Journal of Natural Products,1986,49(1):139-142.

[14] 李国栋,周全,赵长文,等.青蒿素类药物的研究现状[J].中国药学杂志,1998,33(7):385-389.

[15] Warhurst DC, Homewood CA, Baggaley VC. The chemotherapy of rodent malaria. XX. Autophagic vacuole formation in Plasmodium berghei in vitro[J]. Annals of Tropical Medicine and Parasitology,1974,68(3):265-281.

[16] Ye ZG, Li ZL. Effect of Qinghaosu on choloroquine-induced pgment clumping[J]. Journal of Traditional Chinese Medicine, 1981,1(2):105-112.

[17] Desjardins RE, Canfield CJ, Haynes JD, et al. Quantitative assessment of antimalarial activity in in vitro by a semiautomated microdilution technique[J]. Antimicrobial Agents and Chemotherapy,1979,16(6):710-718.

[18] Ye ZG, Van DK, Wimmer M. Effect of artemisinin (qinghaosu) and chloroquine on drug-sensitive and drug-resistant strains of Plasmodium falciparum malaria:use of [2,8-3H]adenosine as an alternative to [G-3H]hypoxanthine in the assessment of in vitro antimalarial activity[J]. Experimental Parasitology,1987,64(3):418-423.

[19] Li ZL, Gu HM, Warhurst DC, et al. Effects of qinghaosu and related compounds on incorporation of [G-3H] hypoxanthine by Plasmodium falciparum in vitro[J]. Transactions of the Royal Society of Tropical Medicine and Hygiene,1983,77(4):522-523.

[20] Gu HM, Warhurst DC, Peters W. Rapid action of Qinghaosu and related drugs on incorporation of [3H] isoleucine by Plasmodium falciparum in vitro[J]. Biochemical Pharmacology,1983,32(17):2463-2466.

[21] Ye ZG, Carolyn D, Knox VD. Selective effect of qinghaosu on different stages of Plasmodium falciparum in vitro[J]. Journal of Chinese Pharmaceutical Sciences,1993,2(1):64-68.

[22] 顾浩明,朱梅英,奚国良,等.13个化合物对伯氏疟原虫珠蛋白酶活性及游离氨基酸活性的影响[J].中国药理学报,1987,8(5):460-464.

[23] 靳永刚,滕翁和,孙存普.自由基与青蒿琥酯毒性机理[J].中国药理学与毒理学杂志,1989,3(2):138-142.

[24] Kamchonwongpaisan S, Meshnick SR. The mode of action of the antimalarial artemisinin and its derivatives[J]. General Pharmacology, 1996,27(4):587-592.

[25] Lee C H, Hong H, Shin J, et al. NMR studies on novel antitumor drug candidates, deoxoartemisinin and carboxypropyldeoxo- artemisinin[J]. Biochemical and Biophysical Research Communications, 2000,274(2):359-369.

[26] 徐进,郑莹,张睿,等.青蒿素类药物作用机制的探讨[J].药学进展,2002, 26(5):274-277.

[27] Li Y, Wu YL. A golden phoenix arising from the herbal nest- A review and reflection on the study of antimalarial drug Qinghaosu[J]. Frontiers of Chemistry in China,2010,5(4):357-422.

[28] Lee P, Ye Z, Van DK, et al. X-Ray Microanalysis of Plasmodium and infected red blood cells:Effects of Qinghaosu and Chloroquine on potassium, sodium, and phosphorus composition[J]. The American Journal of Tropical Medicine and Hygiene,1988,39(2):157-165.

[29] 藏其中,郑振源,齐尚斌,等.青蒿素对免疫功能的调节作用[J].核技术,1984,7(2):55-56.

[30] 庄国康,朱毅,何立文,等.青蒿治疗盘形红斑狼疮[J].新医药学杂志, 1979,8(6):359-362.

相似文献/References:

[1]王乃婕,邱琳,杜丰,等.溶解型青蒿素贴剂的研究[J].中国中医药信息杂志,2009,16(8):41.
 WANG Nai-jie,QIU Lin,DU Feng,et al.Study on Artemisinin Transdermal Delivery Systems[J].zhongguo zhongyiyao xinxi zazhi,2009,16(9):41.
[2]杨凤珍,陈珠峰,魏文斌,等.坦桑尼亚HIV/AIDS患者合并疟疾的中医药治疗[J].中国中医药信息杂志,2009,16(10):77.
 [J].zhongguo zhongyiyao xinxi zazhi,2009,16(9):77.
[3]吕翠岩,陈信义,唐炳华.青蒿素及其衍生物逆转肿瘤耐药作用初探[J].中国中医药信息杂志,2006,13(4):12.
 LU Cui-yan,CHEN Xin-Yi,TANG Bing-hua.A Study in Effect of Artemisinin and its Derivatives on Reversion of Multi-drug Resistance of Tumors[J].zhongguo zhongyiyao xinxi zazhi,2006,13(9):12.
[4]吕茂平,刘瑞华.抗疟疾中药专利申请现状分析和建议[J].中国中医药信息杂志,2016,23(12):18.[doi:10.3969/j.issn.1005-5304.2016.12.005]
 LV Mao-ping,LIU Rui-hua.Analysis and Suggestions of Patent TCM for Anti-malaria[J].zhongguo zhongyiyao xinxi zazhi,2016,23(9):18.[doi:10.3969/j.issn.1005-5304.2016.12.005]
[5]沈硕,刘淑芝,杜茂波.青蒿素类抗疟制剂研究概述[J].中国中医药信息杂志,2015,22(10):125.[doi:10.3969/j.issn.1005-5304.2015.10.039]
 SHEN Shuo,LIU Shu-zhi,DU Mao-bo.Research Progress of Artemisinins-based Antimalarial Agents[J].zhongguo zhongyiyao xinxi zazhi,2015,22(9):125.[doi:10.3969/j.issn.1005-5304.2015.10.039]

备注/Memo

基金项目:科技部重大专项-重大新药创制(2012ZX09202101- 005);中国中医科学院基本科研业务费自主选题重点项目(ZZ0608)

更新日期/Last Update:

2014-08-15