[1]宁冰冰,陈瑜,张腾.三七及其主要皂苷组分在心血管疾病中的作用研究进展[J].中国中医药信息杂志,2017,24(10):126-129.[doi:10.3969/j.issn.1005-5304.2017.10.034]
 NING Bing-bing,CHEN Yu,ZHANG Teng.Research Progress in the Effects of Notoginseng Radix et Rhizoma and Its Main Saponins in Cardiovascular Diseases[J].zhongguo zhongyiyao xinxi zazhi,2017,24(10):126-129.[doi:10.3969/j.issn.1005-5304.2017.10.034]
点击复制

三七及其主要皂苷组分在心血管疾病中的作用研究进展

参考文献/References:

[1] 钟晓凤.三七的药理作用及其临床应用研究[J].中医临床研究,2015, 7(6):116-117.

[2] 张海燕.中药三七治疗心血管疾病的临床分析[J].中西医结合心血管病杂志:电子版,2016,4(11):68-69.

[3] 钱婷婷,郭一迪,何芳.三七粉与阿斯匹林对血小板聚集率检测结果的影响[J].中药药理与临床,2015,31(2):184-185.

[4] 李韬,雷菠,冯丽芬,韦耀东.三七对高脂血症家兔血浆TXB_2、GMP-140含量的影响[J].江苏医药,2012,38(7):763-765.

[5] 周铄,翟桂兰,石月萍.三七预处理对大鼠心肌缺血再灌注损伤的保护作用[J].中国新药杂志,2009,18(8):737-740.

[6] 胡志洁,张志耘.三七总皂苷对心脑血管的药理作用研究[J].天津药学,2006,18(6):51-55.

[7] 阿得力?艾山.三七总皂苷对心肌梗死大鼠血管新生及VEGF表达的影响[J].中西医结合心脑血管病杂志,2016,14(15):1732-1735.

[8] 杨清峰,崔德芝,阎小燕.血栓弹力图评测三七皂苷联合阿司匹林对老年冠心病患者抗栓疗效的影响[J].南京中医药大学学报,2016,32(5):425-427.

[9] 刘桂林,窦迎春,乔云.三七总皂苷对动脉粥样硬化血管内皮的保护作用[J].中西医结合心脑血管病杂志,2013,11(9):1094-1096.

[10] 李娟莉,苏式兵.三七总皂苷对大鼠急性心肌梗死的保护作用[J].中药药理与临床,2013,29(1):68-72.

[11] 姜辉,汪永忠,刘晓闯,等.三七总皂苷对肝纤维化大鼠细胞因子的影响[J].中药材,2013,36(7):1123-1127.

[12] 胡伟平,张燕林.三七总皂苷对腹膜纤维化大鼠转化生长因子-β-1的影响[J].中国中西医结合肾病杂志,2014,12(15):1100-1102.

[13] 周平,王磊,刘彦,等.三七总皂甙对油酸致大鼠肺纤维化的治疗作用机制研究[J].世界最新医学信息文摘,2016,16(94):1-2,4.

[14] 聂丹,孙红丹,时召平,等.丹皮酚、三七总皂苷组方对急性心肌梗死大鼠心脏内Ⅰ、Ⅲ型胶原表达的影响[J].天津医药,2016,44(8):955-958,1059.

[15] KIM J H. Cardiovascular diseases and panax ginseng[J]. Journal of Ginseng Research,2012,1:16-26.

[16] DENG Y, ZHANG T, TENG F, et al. Ginsenoside Rg1 and Rb1, in combination with salvianolic acid B, play different roles in myocardial infarction in rats[J]. J Chin Med Assoc,2015,78(2)114-120.

[17] DENG J, WANG Y W, CHEN W M, et al. Role of nitric oxide in ginsenoside Rg(1)-induced protection against left ventricular hypertrophy produced by abdominal aorta coarctation in rats[J]. Biol Pharm Bull,2010,33(4):631-635.

[18] CHEN H, YIN J, DENG Y, et al. The protective effects of ginsenoside Rg1 against hypertension target-organ damage in spontaneously hypertensive rats[J]. BMC Complement Altern Med, 2012,12:53.

[19] ZHU D, WU L, LI C R, et al. Ginsenoside Rg1 protects rat cardiomyocyte from hypoxia/reoxygenation oxidative injury via antioxidant and intracellular calcium homeostasis[J]. J Cell Biochem,2009,108(1):117-124.

[20] ZHANG Y J, ZHANG X L, LI M H, et al. The ginsenoside Rg1 prevents transverse aortic constriction-induced left ventricular hypertrophy and cardiac dysfunction by inhibiting fibrosis and enhancing angiogenesis[J]. J Cardiovasc Pharmacol,2013,62(1):50-57.

[21] 陈梅卿,李卫华,石桂秀.人参皂苷Rb1对心血管系统的药理作用研究进展[J].医学综述,2015,21(3):519-521.

[22] LI Y H, LI Y Y, FAN G W, et al. Cardioprotection of ginsenoside Rb1 against ischemia/reperfusion injury is associated with mitochondrial permeability transition pore opening inhibition[J]. Chin J Integr Med,2016,22(1):1-10.

[23] YAN X, TIAN J, WU H, et al. Ginsenoside Rb1 protects neonatal rat cardiomyocytes from hypoxia/ischemia induced apoptosis and inhibits activation of the mitochondrial apoptotic pathway[J]. Evid Based Complement Alternat Med,2014(2):149195.

[24] PAN C, HUO Y, AN X, et al. Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation[J]. Vascul Pharmacol,2012,56(3/4):150-158.

[25] HOU Y L, TSAI Y H, LIN Y H, et al. Ginseng extract and ginsenoside Rb1 attenuate carbon tetrachloride-induced liver fibrosis in rats[J]. BMC Complement Altern Med,2014,14:415.

[26] 孔宏亮,宋丽杰,李占全,等.人参皂甙Rb1对阿霉素心力衰竭大鼠致心脏纤维化因子表达的影响[J].南京医科大学学报:自然科学版,2012, 32(1):26-29.

[27] ZHU D, LIU M, YANG Y, et al. Ginsenoside Rd ameliorates experimental autoimmune encephalomyelitis in C57BL/6 mice[J]. J Neurosci Res,2014,92(9):1217-1226.

[28] CONG L, CHEN W. Neuroprotective effect of ginsenoside Rd on spinal cord injury rats[J]. Basic Clin Pharmacol Toxicol,2016, 119(2):193-201.

[29] LU C, SUN Z, WANG L, et al. Inhibition of L-type Ca2+ current by ginsenoside Rd in rat ventricular myocytes[J]. J Ginseng Res, 2015,39(2):169-177.

[30] KIM Y J, YAMABE N, CHOI P, et al. Efficient thermal deglycosylation of ginsenoside Rd and its contribution to the improved anticancer activity of ginseng[J]. J Agric Food Chem, 2013,61(38):9185-9191.

[31] GUAN Y Y, ZHOU J G, ZHANG Z, et al. Ginsenoside-Rd from panax notoginseng blocks Ca2+ influx through receptor- and store-operated Ca2+ channels in vascular smooth muscle cells[J]. Eur J Pharmacol,2006,548(1/2/3):129-136.

[32] ZENG X, LI J, LI Z, et al. Ginsenoside Rd mitigates myocardial ischemia-reperfusion injury via Nrf2/HO-1 signaling pathway[J]. Int J Clin Exp Med,2015,8(8):14497-14504.

[33] WANG Y, LI X, WANG X, et al. Ginsenoside Rd attenuates myocardial ischemia/reperfusion injury via Akt/GSK-3β signaling and inhibition of the mitochondria-dependent apoptotic pathway[J]. PLoS One,2013,8(8):e70956.

[34] YU Y, SUN G, LUO Y. Cardioprotective effects of notoginsenoside R1 against ischemia/reperfusion injuries by regulating oxidative stress- and endoplasmic reticulum stress- related signaling pathways[J]. Sci Rep,2016,6:21730.

[35] JIA C, XIONG M, WANG P, et al. Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model[J]. PLoS One,2014,9(6):e99849.

[36] YANG Y, XI P, XIE Y, et al. Notoginsenoside R1 reduces blood pressure in spontaneously hypertensive rats through a long non-coding RNA AK094457[J]. Int J Clin Exp Pathol,2015,8(3):2700-2709.

[37] XIA K P, CA H M, SHAO C Z. Protective effect of notoginsenoside R1 in a rat model of myocardial ischemia reperfusion injury by regulation of Vitamin D3 upregulated protein 1/NF-κB pathway[J]. Pharmazie,2015,70(11):740-744.

[38] 吴颖,孙冰,肖静,等.三七皂苷R1对LPS诱导的小鼠心肌损伤的保护作用[J].中国药理学通报,2013,29(2):179-184.

[39] 万强,潘芸芸,贾钰华,等.三七皂苷R1抑制JNK通路减轻H2O2诱导心肌细胞损伤的作用[J].时珍国医国药,2015,26(9):2061-2064.

[40] 陈伟伟,高润霖,刘力生,等.《中国心血管病报告2014》概要[J].中国循环杂志,2015,30(7):617-622.

相似文献/References:

[1]唐敏,唐晓玲,指导:陈荣.三七总皂苷治疗心血管疾病临床研究进展[J].中国中医药信息杂志,2006,13(9):93.
 [J].zhongguo zhongyiyao xinxi zazhi,2006,13(10):93.
[2]曹炜,陈凯,王阶.丹参和三七单体成分对干细胞分化的影响[J].中国中医药信息杂志,2010,17(8):106.[doi:10.3969/j.issn.1005-5304.2010.08.061]
 [J].zhongguo zhongyiyao xinxi zazhi,2010,17(10):106.[doi:10.3969/j.issn.1005-5304.2010.08.061]
[3]陆善旦,王建.三七销快价格走高探因[J].中国中医药信息杂志,2009,16(2):112.
 [J].zhongguo zhongyiyao xinxi zazhi,2009,16(10):112.
[4]赵建光.三七为主治疗眼病出血举隅[J].中国中医药信息杂志,2008,15(6):82.
 [J].zhongguo zhongyiyao xinxi zazhi,2008,15(10):82.
[5]张永太,修彦凤,陶建生,等.黄芪、丹参、三七中多糖提取工艺考察[J].中国中医药信息杂志,2011,18(11):65.[doi:10.3969/j.issn.1005-5304.2011.11.026]
 ZHANG Yong-tai,XIU Yan-feng,TAO Jian-sheng,et al.Extraction of Crude Polysaccharide from Radix astragali, Radix salviae miltiorrhizae and Radix notoginseng[J].zhongguo zhongyiyao xinxi zazhi,2011,18(10):65.[doi:10.3969/j.issn.1005-5304.2011.11.026]
[6]赵雪松,陈志刚,高芳,等.三七总皂苷对脑出血大鼠脑含水量和凝血酶的影响[J].中国中医药信息杂志,2014,21(2):46.[doi:10.3969/j.issn.1005-5304.2014.02.013]
 ZHAO Xue-song,CHEN Zhi-gang,GAO Fang,et al.Effect of Panax Notoginseng Saponins on Cerebral Water Content and Thrombin of Intracerebral Hemorrhage Rats[J].zhongguo zhongyiyao xinxi zazhi,2014,21(10):46.[doi:10.3969/j.issn.1005-5304.2014.02.013]
[7]朱海燕,高永红,吴爱明,等.三七总皂苷对铝暴露脑微血管内皮细胞胞质紧密黏连蛋白1表达的影响[J].中国中医药信息杂志,2012,19(9):36.[doi:10.3969/j.issn.1005-5304.2012.09.013]
 ZHU Hai-yan,GAO Yong-hong,WU Ai-ming,et al.Effect of Panax Notoginseng Saponins on Tight Junctional Protein ZO-1 of Brain Microvascular Endothelial Cells Exposed to Aluminum[J].zhongguo zhongyiyao xinxi zazhi,2012,19(10):36.[doi:10.3969/j.issn.1005-5304.2012.09.013]
[8]马红霞,尤昭玲,王若光,等.三七复合有效成分对恒河猴细菌感染性子宫出血 模型内膜组织NF-κB活性的影响[J].中国中医药信息杂志,2004,11(7):599.
 MA Hong-xia,YOU Zhao-ling,WANG Ruo-guang,et al.Influence of Two Kinds of Active Components from Panax Notoginseng on NF-κB Activity in Inflammatory Metrorrhagia Model of Macaca Mulatta[J].zhongguo zhongyiyao xinxi zazhi,2004,11(10):599.
[9]周红海,陈 勇,谢 臻,等.百草痛立消药酒的薄层色谱鉴别[J].中国中医药信息杂志,2005,12(12):46.
 ZHOU Hong-hai,CHEN Yong,XIE Zhen,et al.Study on the Identification of TLC for Baicaotonglixiao Medicinal Wine[J].zhongguo zhongyiyao xinxi zazhi,2005,12(10):46.
[10]杨丽鹍,玛娜璐璐,朱海燕,等.三七总皂苷对β-淀粉样蛋白42损伤脑微血管内皮细胞ZO-1表达的影响[J].中国中医药信息杂志,2014,21(8):57.[doi:10.3969/j.issn.1005-5304.2014.08.016]
 YANG Li-kun,MANA Lulu,ZHU Hai-yan,et al.Effects of Panax Notoginseng Saponins on Expression of ZO-1 of Brain Microvascular Endothelial Cells Caused by Aβ42[J].zhongguo zhongyiyao xinxi zazhi,2014,21(10):57.[doi:10.3969/j.issn.1005-5304.2014.08.016]
[11]谭朝阳,尤昭玲,袁宏佳.三七渗漉提取工艺的研究[J].中国中医药信息杂志,2010,17(4):51.
 TAN Zhao-yang,YOU Zhao-ling,YUAN Hong-jia.Study on Percolation Extraction Process of Panax Notoginseng[J].zhongguo zhongyiyao xinxi zazhi,2010,17(10):51.
[12]宋 茹,袁继民,雷 岚.三七及其制剂HPLC指纹图谱的研究[J].中国中医药信息杂志,2005,12(6):47.
 SONG Ru,YUAN Ji-min,LEI Lan.Study on Fingerprints of Radix Notoginseng and its Preparation by HPLC[J].zhongguo zhongyiyao xinxi zazhi,2005,12(10):47.
[13]宋达,魏鑫,袁云云,等.三七总皂苷治疗脑血管疾病研究进展[J].中国中医药信息杂志,2017,24(8):129.[doi:10.3969/j.issn.1005-5304.2017.08.032]
 SONG Da,WEI Xin,YUAN Yun-yun,et al.Research Progress in Treatment of Cerebral Vascular Disease by Panax Notoginseng Saponins[J].zhongguo zhongyiyao xinxi zazhi,2017,24(10):129.[doi:10.3969/j.issn.1005-5304.2017.08.032]

备注/Memo

基金项目:国家自然科学基金(81273960);上海市优秀学科带头人(14XD1403500);上海市浦江计划(11PJ1409000);上海市东方学者跟踪计划(GZ2015011);上海市高校特聘教授(东方学者)人才计划(2011年);上海市085一流学科建设科技创新支持计划(085ZY1212,085ZY1221)

更新日期/Last Update:

2017-09-18