[1]杨晓利,瞿惠燕,戎靖枫,等.基于TGF-β1/Smads通路的鹿红方对心肌梗死后心力衰竭大鼠心肌纤维化的影响[J].中国中医药信息杂志,2021,28(9):92-98.[doi:10.19879/j.cnki.1005-5304.202104414]
 YANG Xiaoli,QU Huiyan,RONG Jingfeng,et al.Effects of Luhong Prescription on Myocardial Fibrosis in Rats with Heart Failure After Myocardial Infarction Based on TGF-1/Smads Pathway[J].zhongguo zhongyiyao xinxi zazhi,2021,28(9):92-98.[doi:10.19879/j.cnki.1005-5304.202104414]
点击复制

基于TGF-β1/Smads通路的鹿红方对心肌梗死后心力衰竭大鼠心肌纤维化的影响

参考文献/References:

[1] KURMANI S, SQUIRE I. Acute heart failure:definition, classification and epidemiology[J]. Curr Heart Fail Rep,2017, 14(5):385-392.

[2] 王宙,周琳,刘洋,等.慢性心力衰竭的流行病学研究现状及其防治研究进展[J].中国循证心血管医学杂志,2019,11(8):1022-1024.

[3] XUE K E, ZHANG J, LI C, et al. The role and mechanism of transforming growth factor beta 3 in human myocardial infarction-induced myocardial fibrosis[J]. J Cell Mol Med,2019,132:4229-4243.

[4] EULER G. Good and bad sides of TGFβ-signaling in myocardial infarction[J]. Front Physiol,2015(6):66.

[5] WANG D M, JIN J J, TIAN L M, et al. MiR-195 Promotes myocardial fibrosis in MI rats via targeting TGF-β1/Smad[J]. J Biol Regul Homeost Agents,2020(34):1325-1332.

[6] YOUSEFI F, SHABANINEJAD Z, VAKILI S, et al. TGF-β and WNT signaling pathways in cardiac fibrosis:non-coding RNAs come into focus[J]. Cell Commun Signal,2020,18(1):87.

[7] YOUSEFI F, SOLTANI B M, RABBANI S. MicroRNA-331 inhibits isoproterenol-induced expression of profibrotic genes in cardiac myofibroblasts via the TGF-β/smad3 signaling pathway[J]. Sci Rep,2021,11(1):2548.

[8] 徐基杰,瞿惠燕,戎靖枫,等.鹿红方对慢性心力衰竭伴心肌纤维化影响的临床研究[J].上海中医药杂志,2017,51(S1):48-51.

[9] YANG T, QU H, SONG X, et al. Luhong Granules prevent ventricular remodelling after myocardial infarction by reducing the metabolites TMAO and LPS of the intestinal flora[J]. Evid Based Complement Alternat Med,2019,2019:8937427.

[10] QU H, WANG Y, YANG T, et al. Luhong formula inhibits myocardial fibrosis in a paracrine manner by activating the gp130/JAK2/STAT3 pathway in cardiomyocytes[J]. J EthnoPharmacol,2017,202:28-37.

[11] 刘茜,周华,瞿惠燕,等.鹿红颗粒对心力衰竭大鼠心功能的影响[J].上海中医药大学学报,2017,31(3):62-66.

[12] 莫新玲,谢福生,严冬雪,等.冠状动脉结扎与腹主动脉缩窄所致慢性心力衰竭大鼠模型比较[J].华夏医学,2009,22(1):4-6.

[13] ZHU M J, WANG Y P, XIE S Y, et al. Protective effects of Jiashen Prescription on myocardial infarction in rats[J]. Chin J Integr Med,2015,21(6):417-422.

[14] 钟泽,罗秀英,刘桂林,等.SD大鼠3种慢性心力衰竭模型的建立及心功能比较[J].心电与循环,2014,33(4):307-310.

[15] 黄继汉,黄晓晖,陈志扬,等.药理试验中动物间和动物与人体间的等效剂量换算[J].中国临床药理学与治疗学,2004,9(9):1069-1072.

[16] HEUSCH G, LIBBY P, GERSH B, et al. Cardiovascular remodelling in coronary artery disease and heart failure[J]. Lancet,2014, 383(3):1933-1943.

[17] KONG P, CHRISTIA P, FRANGOGIANNIS N G. The pathogenesis of cardiac fibrosis[J]. Cell Mol Life Sci,2014,71(4):549-574.

[18] HANNA A, FRANGOGIANNIS N G. The role of the TGF-β superfamily in myocardial infarction[J]. Front Cardiovasc Med,2019,9(6):140.

[19] JIN D X, HAN F F. FOXF1 ameliorates angiotensinⅡ-induced cardiac fibrosis in cardiac fibroblasts through inhibiting the TGF-β1/Smad3 signaling pathway[J]. J Recept Signal Transduct Res,2020,40(6):493-500.

[20] HAN A B, LU Y D, ZHENG Q, et al. Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction[J]. Cell Physiol Biochen,2018,45(5):1797-1806.

[21] CHEN K Y, CHEN W, LIU S L, et al. Epigallocatechingallate attenuates myocardial injury in a mouse model of heart failure through TGF-β1/Smad3 signaling pathway[J]. Mol Med Rep,2018, 17(6):7652-7660.

[22] HUANG S B, CHEN B J, SU Y A, et al. Distinct roles of myofibroblast-specific Smad2 and Smad3 signaling in repair and remodeling of the infarcted heart[J]. J Mol Cell Cardiol,2019, 132:84-97.

[23] YUAN S M, JING H. Cardiac pathologies in relation to Smad- dependent pathways[J]. Interact Cardiovasc Thorac Surg,2010, 11(4):455-460.

[24] 刘茜,周华,戎靖枫,等.鹿红颗粒治疗冠状动脉粥样硬化性心脏病合并心功能不全的临床研究[J].中西医结合心脑血管病杂志,2015, 13(7):867-870.

[25] 杨天舒,瞿惠燕,戎靖枫,等.鹿红颗粒对心肌缺血再灌注损伤大鼠肠道菌群的影响[J].中西医结合心脑血管病杂志,2021,19(3):418- 422.

[26] 戎靖枫,封舟,刘茜,等.鹿红方对心力衰竭大鼠过氧化物酶增殖物激活受体和心肌组织的影响[J].中西医结合心脑血管病杂志,2017, 15(3):293-297.

[27] 徐基杰,瞿惠燕,戎靖枫,等.鹿红颗粒对心力衰竭大鼠血流动力学及血浆血管紧张素Ⅱ和醛固酮的影响[J].上海中医药大学学报,2015, 29(5):53-56.

[28] 蔡辉,胡婉英,王艳君,等.鹿角方治疗充血性心力衰竭疗效观察[J].安徽中医学院学报,2002,21(4):11-15.

[29] HAN C K, TIEN Y C, HSIEH D J Y, et al. Attenuation of the LPS-induced, ERK-mediated upregulation of fibrosis-related factors FGF-2, uPA, MMP-2, and MMP-9 by Carthamus tinctorius L in cardiomyoblasts[J]. Environ Toxicol,2017,32(3):754-763.

[30] 庄华梅,陈秀娇,王俊芳,等.补骨脂对慢性心力衰竭大鼠心肌损伤的影响[J].中西医结合心脑血管病杂志,2021,19(6):930-934.

[31] 周艳,高洁,柴艺汇,等.淫羊藿苷抗心肌重塑的作用机制[J].湖北民族大学学报(医学版),2020,37(4):44-47.

[32] 蔡辉,胡婉英,王艳君,等.鹿角方逆转充血性心力衰竭大鼠心肌纤维化的机理研究[J].广州中医药大学学报,2002,19(3):199-203.

备注/Memo

基金项目:国家自然科学基金面上项目(81673753);上海中医药大学研究生创新创业能力培养项目(Y201916);上海市科学技术委员会科技支撑项目(18401932800);上海市申康医学发展中心三年行动计划(SHDC2020CR1053B)

更新日期/Last Update:

2021-08-18