[1]朱青春,崔国红,邵水金,等.阿尔茨海默病大鼠自噬相关蛋白Beclin-1和凋亡相关蛋白p53表达变化及电针的调控作用[J].中国中医药信息杂志,2014,21(9):68-71.[doi:10.3969/j.issn.1005-5304.2014.09.020]
 ZHU Qing-chun,CUI Guo-hong,SHAO Shui-jin,et al.Expression Changes of Autophagy Associated Protein Beclin-1 and Apoptosis Associated Protein p53 in Rats with Alzheimer’s Disease and Regulatory Effects of Electroacupuncture[J].zhongguo zhongyiyao xinxi zazhi,2014,21(9):68-71.[doi:10.3969/j.issn.1005-5304.2014.09.020]
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阿尔茨海默病大鼠自噬相关蛋白Beclin-1和凋亡相关蛋白p53表达变化及电针的调控作用

参考文献/References:

[1] Mizushima N, Levine B, Cuervo AM, et al. Autophagy fights disease through cellular self-digestion[J]. Nature,2008,451(7182):1069- 1075.

[2] Pickford F, Masliah E, Britschgi M, et al. The autophagy-related protein Bclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid β accumulation in mice[J]. J Clin Invest,2008,118(6):2190-2199.

[3] Tan CC, Yu JT, Tan MS, et al. Autophagy in aging and neurodegenerative diseases:implications for pathogenesis and therapy[J]. Neurobiol Aging,2014,35(5):941-957.

[4] Hung SY, Huang WP, Liou HC, et al. Autophagy protects neuron from Aβ-induced cytotoxicity[J]. Autophagy,2009,5(4):502-510.

[5] Cheung YT, Zhang NQ, Hung CH, et al. Temporal relationship of autophagy and apoptosis in neurons challenged by low molecular weight β-amyloid peptide[J]. J Cell Mol Med,2011,15(2):244-257.

[6] 代渊,王飞,徐世军.中医治疗阿尔茨海默病优势述略[J].中国中医药信息杂志,2010,17(8):5-6.

[7] 国海东,邵水金,朱晶,等.电针对阿尔茨海默病大鼠学习记忆力改善及海马神经元损伤保护的作用及机制[J].上海针灸杂志,2012,31(9):682-685.

[8] Frautschy SA, Yang F, Calderón L, et al. Rodent models of Alzheimer’s disease: rat A beta infusion approaches to amyloid deposits[J]. Neurobiol Aging,1996,17(2):311-321.

[9] 李忠仁.实验针灸学[M].北京:中国中医药出版社,2003:241-248.

[10] Jovanovi? Z. Mechanisms of neurodegeneration in Alzheimer’s disease[J]. Med Pregl,2012,65(7/8):301-307.

[11] 国海东,国海光,邵水金.自噬在阿尔茨海默病中的作用及其机制[J].生理科学进展,2011,42(5):398-401.

[12] Dorszewska J, Oczkowska A, Suwalska M, et al. Mutations in the exon 7 of Trp53 gene and the level of p53 protein in double transgenic mouse model of Alzheimer’s disease[J]. Folia Neuropathol,2014,52(1):30-40.

[13] 刘金凤,张莹,孙金平,等.针刺疗法对老年痴呆小鼠脑内p53蛋白表达的影响[J].中国中西医结合杂志,2013,33(10):1367-1371.

[14] Sebti S, Prébois C, Pérez-Gracia E, et al. BAT3 modulates p300-dependent acetylation of p53 and autophagy-related protein 7 (ATG7) during autophagy[J]. Proc Natl Acad Sci USA,2014, 111(11):4115-4120.

[15] Liu J, Xia H, Kim M, et al. Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13[J]. Cell,2011,147(1):223-234.

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备注/Memo

基金项目:国家自然科学基金(81102670);上海市高校青年教师专项基金(shzy015);上海中医药大学名师传承研究工程项目(2009120)

更新日期/Last Update:

2014-08-15