[1]郇鹏飞,金智生,高钰莹,等.基于肠道微生态探讨2型糖尿病从脾虚论治机理[J].中国中医药信息杂志,2019,26(5):8-10.[doi:10.3969/j.issn.1005-5304.2019.05.002]
 HUAN Pengfei,JIN Zhisheng,GAO Yuying,et al.Study on Mechanism of Treating Type 2 Diabetes from Spleen DeficiencyBased on Intestinal Microecology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(5):8-10.[doi:10.3969/j.issn.1005-5304.2019.05.002]
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基于肠道微生态探讨2型糖尿病从脾虚论治机理

参考文献/References:

[1] 高艺家,杨晓航.2型糖尿病与肠道菌群相关性研究进展[J].世界最新医学信息文摘,2016,16(48):45.
[2] 李吉武,李双蕾,唐爱华,等.2型糖尿病的中医病机与肠道菌群的研究进展[J].世界中西医结合杂志,2016,11(4):585-588.
[3] DUNCAN S H, BELENGUER A L, HOLTROP G R, et a1. Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces[J]. Appl Environ Microbiol,2007,73(4):1073-1078.
[4] TALUKDAR S, OLEFSKV J M, OSBORN O. Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases[J]. Trends Pharmacol Sci,2011,32(9):543- 550.
[5] 陈新君.复方四君子汤及党参多糖调节溃疡性结肠炎小鼠肠道菌群的作用研究[D].兰州:兰州大学,2016.
[6] CREELY S J, MCTERNAN P G, KUSMINSKI C M, et al. Lipopolysaccharide activates an innate immune system respouse in human adipose tissue in obesity and type 2 diabetes[J]. Am J Physiol Endocrinol Metab,2007,292(3):E740-E747.
[7] CANI P D, BIBILONI R, KNAUF C. et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice[J]. Diabetes,2008, 57(6):1470-1481.
[8] 李春香,李显彬,李丽秋,等.蒙古黄芪两种不同成分提取物对肠道微生态失调小鼠的调节作用[J].中国微生态杂志,2010,22(1):14-20.
[9] 陈伟仁.香砂六君子丸对脾虚痰浊大鼠胃肠粘膜细胞JAK2/STAT3通路的影响[D].沈阳:辽宁中医药大学,2014.
[10] DELZENNE N M, CANI P D. Nutritional modulation of gut microbiota in the context of obesity and insulin resistance:Potential interest of prebioties[J]. Int Dairy Journal,2010,20(2):277-280.
[11] 张洁,冷萍.参苓组方对2型糖尿病大鼠胰岛素样生长因子1干预作用的研究[J].中国糖尿病杂志,2011,19(3):201-203.
[12] 吴三明,张万岱.脾虚泄泻患者肠道微生态学的初步研究[J].中国中西医结合脾胃杂志,1996,4(4):203-204.
[13] EWASCHUK J B, DIELEMAN L A. Probiotics and prebiotics in chronic inflammatory bowel diseases[J]. World J Gastroenterol,2006, 12(37):5941-5950.
[14] 丁维俊,周邦靖,翟慕东,等.参苓白术散对小鼠脾虚模型肠道菌群的影响[J].北京中医药大学学报,2006,29(8):530-533.
[15] 师林,柯斌,罗晓莉.从脾虚痰湿角度探讨2型糖尿病胰岛素抵抗的中医研究思路[J].广州中医药大学学报,2015,32(2):336-338.(收稿日期:2018-03-25)(修回日期:2018-05-29;编辑:梅智胜)

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备注/Memo

基金项目:国家自然科学基金地区基金(81660777)
通讯作者:金智生,E-mail:jzsgszy@126.com

更新日期/Last Update:

2019-04-21