[1]唐标,唐文静,邓常清.基于网络药理学的黄芪和三七主要有效成分配伍抗缺血性脑损伤作用机制研究[J].中国中医药信息杂志,2019,26(7):109-113.[doi:10.3969/j.issn.1005-5304.2019.07.024]
 TANG Biao,TANG Wenjing,DENG Changqing.Study on Mechanism of Compatibility of Main Active Components of Astragali Radix and Notoginseng Radix et Rhizoma on Cerebral Ischemic Injury Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(7):109-113.[doi:10.3969/j.issn.1005-5304.2019.07.024]
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基于网络药理学的黄芪和三七主要有效成分配伍抗缺血性脑损伤作用机制研究

参考文献/References:

[1] WANG H L, ZHOU Q H, XU M B, et al. Astragaloside Ⅳ for experimental focal cerebral ischemia:preclinical evidence and possible mechanisms[J]. Oxid Med Cell Longev,2017,2017:8424326.
[2] SON H Y, HAN H S, JUNG H W, et al. Panax notoginseng attenuates the infarct volume in rat ischemic brain and the inflammatory response of microglia[J]. J Pharmacol Sci,2009,109:368-379.
[3] 谭华,黄小平,陈北阳,等.黄芪总苷和三七总皂苷配伍对小鼠脑缺血再灌注脑组织氧化应激的影响[J].中西医结合学报,2010,8(5):448-451.
[4] 黄小平,谭华,陈北阳,等.黄芪总苷和三七总皂苷配伍对脑缺血再灌注后MMP-9和TIMP-1表达的影响[J].中国中药杂志,2010,35(16):2187-2191.
[5] 黄小平,邓常清,邱咏园,等.黄芪甲苷和三七的三种有效成分配伍对小鼠脑缺血再灌注后氧化应激和Nrf2/HO-1途径的影响[J].中国药理学通报,2013,29(11):1596-1601.
[6] HUANG X P, QIU Y Y, WANG B, et al. Effects of astragaloside Ⅳ combined with the active components of panax notoginseng on oxidative stress injury and nuclear factor-erythroid 2-related factor 2/heme oxygenase-1 signaling pathway after cerebral ischemia-reperfusion in mice[J]. Pharmacogn Mag,2014,10:402- 409.
[7] HUANG X P, DING H, LU J D, et al. Effects of the combination of the main active components of astragalus and panax notoginseng on inflammation and apoptosis of nerve cell after cerebral ischemia-reperfusion[J]. Am J Chin Med,2015,43:1419-1438.
[8] WANG S, WANG H, LU Y. Tianfoshen oral liquid:a CFDA approved clinical traditional Chinese medicine, normalizes major cellular pathways disordered during colorectal carcinogenesis[J]. Oncotarget,2017,8:14549-14569.
[9] DENNIS G, SHERMAN B T, HOSACK D A, et al. DAVID:database for annotation, visualization, and integrated discovery[J]. Genome Biol,2003,4:R60.
[10] YANG Y, GAO K, HU Z, et al. Autophagy upregulation and apoptosis downregulation in DAHP and triptolide treated cerebral ischemia[J]. Mediators Inflamm,2015,2015:120198.
[11] LIU M, TANG L, LIU X, et al. An evidence-based review of related metabolites and metabolic network research on cerebral ischemia[J]. Oxid Med Cell Longev,2016,2016:9162074.
[12] ZHOU J, DU T, LI B, et al. Crosstalk between MAPK/ERK and PI3K/AKT signal pathways during brain ischemia/reperfusion[J]. ASN Neuro,2015,7:1759091415602463.
[13] TONCHEV A B. Brain ischemia, neurogenesis, and neurotrophic receptor expression in primates[J]. Arch Ital Biol,2011,149:225-231.
[14] VIDALE S, CONSOLI A, ARNABOLDI M, et al. Postischemic inflammation in acute stroke[J]. J Clin Neurol,2017,13:1-9.
[15] WU C, CHEN J, CHEN C, et al. Wnt/β-catenin coupled with HIF-1α/VEGF signaling pathways involved in galangin neurovascular unit protection from focal cerebral ischemia[J]. Sci Rep,2015,5:16151.
[16] HUANG X P, DING H, YANG X Q, et al. Synergism and mechanism of astragaloside Ⅳ combined with ginsenoside Rg1 against autophagic injury of PC12 cells induced by oxygen glucose deprivation/reoxygenation[J]. Biomed Pharmacother,2017,89:124- 134.
[17] FANN D Y, SANTRO T, MANZANERO S, et al. Intermittent fasting attenuates inflammasome activity in ischemic stroke[J]. Exp Neurol,2014,257:114-119.
[18] FANN D Y, LIM Y A, CHENG Y L, et al. Evidence that NF-κB and MAPK signaling promotes NLRP inflammasome activation in neurons following ischemic stroke[J]. Mol Neurobiol,2018,55(2):1082-1096.

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备注/Memo

基金项目:国家自然科学基金(81503385)

更新日期/Last Update:

2019-06-20