[1]赵炳聪,李亚鸿,解红霞.网络药理学在中药复方作用机制研究中的应用[J].中国中医药信息杂志,2020,27(3):133-136.[doi:10.3969/j.issn.1005-5304.201904311]
 ZHAO Bingcong,LI Yahong,XIE Hongxia.Application of Network Pharmacology in Research on Mechanism of Action of TCM Compounds[J].zhongguo zhongyiyao xinxi zazhi,2020,27(3):133-136.[doi:10.3969/j.issn.1005-5304.201904311]
点击复制

网络药理学在中药复方作用机制研究中的应用

参考文献/References:

[1] YILDIRIM M A, GOH K I, CUSICK M E, et al. Drug-targetnetwork[J]. Nat Biotechnol,2007,25(10):1119-1126.

[2] HOPKINS A L. Network pharmacology[J]. Nat Biotechnol,2007, 25(10):1110-1111.

[3] 李泮霖,苏薇薇.网络药理学在中药研究中的最新应用进展[J].中草药,2016,47(16):2938-2942.

[4] TAO W, XU X, WANG X, et al. Network pharmacology-based prediction of the active ingredients and potential targets of Chinese herbal Radix Curcumae formula for application to cardiovascular disease[J]. J Ethnopharmacol,2013,145(1):1-10.

[5] LI X, XU X, WANG J, et al. A system-level investigation into the mechanisms of Chinese traditional medicine: compound Danshen formula for cardiovascular disease treatment[J]. PLoS One,2012, 7:e43918.

[6] XU X, ZHANG W, HUANG C, et al. A novel chemometric method for prediction of human oral bioavailability[J]. Int J Mol Sci,2012, 13(6):69646982.

[7] 李康宁,王蕾,于佳佳,等.基于网络药理学的补肾益髓胶囊治疗多发性硬化机制研究[J].中国中医药信息杂志,2019,26(5):98-104.

[8] 张欢欢,刘寒,向净匀,等.基于网络药理学的四逆汤抗心肌缺血损伤的分子机制研究[J].中国现代中药,2018,20(3):265-277.

[9] 刘洪,范欣生.三拗汤主要功效成分多靶点网络构建[J].中草药,2015,46(22):3370-3376.

[10] 刘培,段金廒,白钢,等.用于妇科血瘀证原发性痛经的四物汤类方主要活性成分网络药理学分析[J].中国中药杂志,2014,39(1):113-120.

[11] YU J G, GUO J, ZHU K Y, et al. How impaired efficacy happened between Gancao and Yuanhua:Compounds, targets and pathways[J]. Sci Rep,2017,7:3828.

[12] 衡霞,朱宝杰,孙莉敏,等.基于网络药理学的黄连解毒汤调节巨噬细胞炎症反应和代谢的作用机制研究[J].药学学报,2018,53(9):1449-1457.

[13] 雷伟,邓艳芳,姜民,等.速效救心丸治疗心肌缺血疾病的网络药理学研究[J].世界科学技术-中医药现代化,2018,20(1):7-16.

[14] 宋祯彦,陈易璇,余婧萍,等.钩藤散活性成分治疗阿尔茨海默病作用机制的网络药理学分析[J].中草药,2018,49(24):5854-5864.

[15] 范荣荣,罗子清,唐丽娟,等.基于网络药理学的小青龙汤治疗支气管哮喘作用机制分析[J].中药新药与临床药理,2019,30(1):52-59.

[16] CHENG L, PAN G F, ZHANG X D, et al. Yindanxinnaotong, a Chinese compound medicine, synergistically attenuates atherosclerosis progress[J]. Sci Rep,2015,5:12333.

[17] 彭艳红,蒋亦昕,白光,等.胃炎康方对慢性非萎缩性胃炎患者胃泌素相关基因调控通路影响[J].中国中医药信息杂志,2019,26(2):42-46.

[18] WANG N, ZHENG Y, GU J, et al. Network-pharmacology-based validation of TAMS/CXCL-1 as key mediator of XIAOPI formula preventing breast cancer development and metastasis[J]. Sci Rep, 2017,7:14513.

[19] 韩彦琪,许浚,张喜民,等.基于网络药理学的元胡止痛滴丸治疗原发性痛经的作用机制研究[J].药学学报,2016,51(3):380-387.

[20] 韩彦琪,孟凡翠,许浚,等.基于网络药理学方法的元胡止痛滴丸治疗原发性痛经的配伍合理性研究[J].中草药,2017,48(3):526-532.

[21] 许海燕,彭修娟,陈衍斌,等.基于网络药理学的“柴胡-黄芩”药对治疗糖尿病的“理法-方药-成分-靶标-活性”关联研究[J].药学学报, 2018,53(9):1414-1421.

[22] 刘夫艳,唐德才,谭喜莹.黄芪-莪术药对基于网络药理学的抗大肠癌分子机制[J].中国实验方剂学杂志,2019,25(13):176-185.

[23] 杨凯麟,曾柳庭,葛安琪,等.基于网络药理学探讨桃仁-红花药对活血化瘀的分子机制[J].世界科学技术-中医药现代化,2018,20(12):2208-2216.

[24] 吴嘉瑞,金燕萍,王凯欢,等.基于网络药理学的“金银花-连翘”药对作用机制分析[J].中国实验方剂学杂志,2017,23(5):179-183.

[25] 陶瑾,姜民,陈露莹,等.基于中药性味理论和网络药理学方法的治疗消渴方药作用机制研究[J].药学学报,2017,52(2):236-244.

[26] 王倩,袁莉莉,张永玲,等.石菖蒲-郁金配伍治疗癫痫的网络药理学研究[J].中国中药杂志,2019,44(13):2701-2708.

[27] 高耀,高丽,高晓霞,等.基于网络药理学的逍遥散抗抑郁活性成分作用靶点研究[J].药学学报,2015,50(12):1589-1595.

[28] 高耀,吴丹,田俊生,等.逍遥散和开心散“同病异治”抑郁症的网络药理学作用机制研究[J].中草药,2018,49(15):3483-3492.

[29] 蔡菲菲,李晓燕,董姝,等.基于网络药理学的茵陈蒿汤“异病同治”研究[J].世界科学技术-中医药现代化,2016,18(9):1507-1514.

[30] 刘志强,王博龙.基于网络药理学预测二妙丸“一方多效”的分子机制[J].中国实验方剂学杂志,2018,24(18):198-206.

[31] 朱虹宇,李红品,高兴,等.交泰丸对糖尿病、抑郁和失眠症“异病同治”的网络药理学机制分析[J].世界科学技术-中医药现代化, 2018,20(3):460-467.

[32] 杨梦蝶,蔡菲菲,武容,等.一贯煎“异病同治”的网络药理学分析[J].世界科学技术-中医药现代化,2017,19(12):1912-1919.

[33] 吴丹,高耀,向欢,等.逍遥散“异病同治”抑郁症和糖尿病的网络药理学作用机制研究[J].中草药,2019,50(8):1818-1827.

[34] 张晓囡,张军平,徐士欣,等.基于网络药理学的黄连解毒汤治疗高血压潜在机制研究[J].中草药,2018,49(24):5865-5875.

[35] 孙莉敏,刘丽芳,朱华旭,等.基于网络药理学的黄连解毒汤治疗阿尔兹海默症的作用机制研究[J].药学学报,2017,52(8):1268-1275.

相似文献/References:

[1]张贵彪,陈启龙,苏式兵?.中药网络药理学研究进展[J].中国中医药信息杂志,2013,20(8):103.[doi:10.3969/j.issn.1005-5304.2013.08.049]
 [J].zhongguo zhongyiyao xinxi zazhi,2013,20(3):103.[doi:10.3969/j.issn.1005-5304.2013.08.049]
[2]李从林,王博龙.基于网络药理学的益母草作用机制分析[J].中国中医药信息杂志,2018,25(12):102.[doi:10.3969/j.issn.1005-5304.2018.12.024]
 LI Cong-lin,WANG Bo-long.Analysis on Mechanism of Effects of Leonu ri Herba Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2018,25(3):102.[doi:10.3969/j.issn.1005-5304.2018.12.024]
[3]彭艳红,蒋亦昕,白光,等.胃炎康方对慢性非萎缩性胃炎患者胃泌素相关基因调控通路影响[J].中国中医药信息杂志,2019,26(2):42.[doi:10.3969/j.issn.1005-5304.2019.02.010]
 PENG Yanhong,JIANG Yixin,BAI Guang,et al.Effect of Weiyankang Prescription on Gastrin-related Gene Regulation Pathway of Chronic Non-atrophic Gastritis[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):42.[doi:10.3969/j.issn.1005-5304.2019.02.010]
[4]严卿莹,叶晔,冯冠,等.基于网络药理学的虎杖治疗结直肠癌作用机制研究[J].中国中医药信息杂志,2019,26(4):96.[doi:10.3969/j.issn.1005-5304.2019.04.020]
 YAN Qingying,YE Ye,FENG Guan,et al.Study on Mechanism of Polygoni Cuspidati Rhizoma et Radix in Treatment of Colorectal Cancer Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):96.[doi:10.3969/j.issn.1005-5304.2019.04.020]
[5]李康宁,王蕾,于佳佳,等.基于网络药理学的补肾益髓胶囊治疗多发性硬化机制研究[J].中国中医药信息杂志,2019,26(5):98.[doi:10.3969/j.issn.1005-5304.2019.05.021]
 LI Kangning,WANG Lei,YU Jiajia,et al.Mechanism Study on Bushen Yisui Capsules for Treatment of Multiple Sclerosis Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):98.[doi:10.3969/j.issn.1005-5304.2019.05.021]
[6]李金霞,指导:曹洪欣.基于复杂网络的温心方治疗冠状动脉狭窄机制研究[J].中国中医药信息杂志,2019,26(6):101.[doi:10.3969/j.issn.1005-5304.2019.06.021]
 LI Jinxia,Instructor: CAO Hongxin.Study on Mechanism of Wenxin Decoction in Treating Coronary Artery Stenosis Based on Complex Network[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):101.[doi:10.3969/j.issn.1005-5304.2019.06.021]
[7]唐标,唐文静,邓常清.基于网络药理学的黄芪和三七主要有效成分配伍抗缺血性脑损伤作用机制研究[J].中国中医药信息杂志,2019,26(7):109.[doi:10.3969/j.issn.1005-5304.2019.07.024]
 TANG Biao,TANG Wenjing,DENG Changqing.Study on Mechanism of Compatibility of Main Active Components of Astragali Radix and Notoginseng Radix et Rhizoma on Cerebral Ischemic Injury Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):109.[doi:10.3969/j.issn.1005-5304.2019.07.024]
[8]刘云娣,高佳珠,杨智华,等.基于网络药理学的补肾益心片治疗高血压分子机制研究[J].中国中医药信息杂志,2019,26(8):104.[doi:10.3969/j.issn.1005-5304.2019.08.021]
 LIU Yundi,GAO Jiazhu,YANG Zhihua,et al.Study on Molecules Mechanism of Bushen Yixin Tablets for Hypertension Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):104.[doi:10.3969/j.issn.1005-5304.2019.08.021]
[9]王韧,樊启猛,李文姣,等.基于网络药理学的鱼腥草治疗支气管炎作用机制研究[J].中国中医药信息杂志,2019,26(10):91.[doi:10.3969/j.issn.1005-5304.2019.10.020]
 WANG Ren,FAN Qimeng,LI Wenjiao,et al.Study on Mechanism of Houttuyniae Herba for Treatment of Bonchitis Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):91.[doi:10.3969/j.issn.1005-5304.2019.10.020]
[10]李冰涛,章辉,肖思雨,等.基于网络药理学的葛根治疗冠心病作用机制研究[J].中国中医药信息杂志,2019,26(10):96.[doi:10.3969/j.issn.1005-5304.2019.10.021]
 LI Bingtao,ZHANG Hui,XIAO Siyu,et al.Study on Mechanism of Puerariae Lobatae Radix in Treating Coronary Heart Disease Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2019,26(3):96.[doi:10.3969/j.issn.1005-5304.2019.10.021]

备注/Memo

基金项目:内蒙古自治区自然科学基金(2018LH08033);内蒙古自治区科技计划项目(kjt15sf24);内蒙古医科大学“医院制剂研发”创新团队(2017年)

更新日期/Last Update:

2020-02-23