[1]陈晶,邵先明,侯志涛.基于网络药理学的黄芪-山药药对治疗2型糖尿病作用机制研究[J].中国中医药信息杂志,2020,27(6):89-95.[doi:10.3969/j.issn.1005-5304.201904077]
 CHEN Jing,SHAO Xianming,HOU Zhitao.Study on Mechanism of Astragali Radix - Dioscoreae Rhizoma in Treatment of Type 2 Diabetes Mellitus Based on Network Pharmacology[J].zhongguo zhongyiyao xinxi zazhi,2020,27(6):89-95.[doi:10.3969/j.issn.1005-5304.201904077]
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基于网络药理学的黄芪-山药药对治疗2型糖尿病作用机制研究

参考文献/References:

[1] 国家药典委员会.中华人民共和国药典:一部[M].北京:中国医药科技出版社,2015.

[2] LI Y, WANG J H, WANG Y H, et al. A systems pharmacology approach to investigate the mechanisms of action of Semen Strychni and Tripterygium wilfordii Hook F for treatment of rheumatoid arthritis[J]. Journal of Ethnopharmacology,2015,175:301-314.

[3] 中华医学会糖尿病学分会.中国2型糖尿病防治指南(2017年版)[J].中国实用内科杂志,2018,38(4):292-344.

[4] 刘洋,杜婧,沈颜红.10种药用黄芪属植物化学成分及药理作用的研究进展[J].中国实验方剂学杂志,2017,23(18):222-234.

[5] 李楠,范颖,贾旭鸣,等.黄芪不同有效部位对糖尿病模型大鼠血清胰岛素、脂联素的影响[J].中国实验方剂学杂志,2011,17(5):144-146.

[6] 孙晓生,谢波.山药药理作用的研究进展[J].中药新药与临床药理, 2011,22(3):353-355.

[7] 周滢,舒承倩,唐欣,等.山药和黄芪的临床配伍意义分析及应用[J].中国中医基础医学杂志,2017,23(9):1332-1333.

[8] 李晓晶,刘瑾,隋在云.黄芪和山药配伍微粉对糖尿病肾病大鼠的保护作用[J].时珍国医国药,2014,25(1):46-48.

[9] 吴嘉瑞,王凯欢,纪凯,等.基于数据挖掘的中医治疗糖尿病处方用药规律分析[J].中国实验方剂学杂志,2015,21(22):214-217.

[10] 田同良,位梦霞.基于数据挖掘方法对周仲瑛治疗糖尿病医案处方用药配伍规律及其病机分析[J].中国中医基础医学杂志,2019,25(3):337-339,352.

[11] 周楚山,徐国峰.名老中医李可治疗糖尿病经验[J].天津中医药大学学报,2018,37(6):455-458.

[12] ZHU J, GU H, LV X, et al. LINC-PINT Activates the mitogen- activated protein kinase pathway to promote acute myocardial infarction by regulating miR-208a-3p[J]. Circulation Journal, 2018,82(11):2783-2792.

[13] YOUN J Y, ZHOU J, CAI H. Bone morphogenic protein 4 mediates NOX1-dependent eNOS uncoupling, endothelial dysfunction, and COX2 induction in type 2 diabetes mellitus[J]. Molecular Endocrinology,2015,29(8):1123-1133.

[14] OZBAYER C, KEBAPCI M N, DEGIMENCI I, et al. Genetic variant in the 3-untranslated region of the COX2 gene is associated with type 2 diabetes:A hospital-based case-control study[J]. Prostaglandins, Leukotrienes and Essential Fatty Acids,2018,13739-42

[15] VERMA S, CHANDRA H, BANERJEE M. Cyclooxygenase 1 (COX1) expression in type 2 diabetes mellitus:A preliminary study from north India[J]. Egyptian Journal of Medical Human Genetics,2016, 17(1):41-45.

[16] 沈志祥,朱立勋,徐伟红.有氧运动对2型糖尿病大鼠AGE-RAGE轴及NF-κB通路的影响[J].昆明医科大学学报,2018,39(1):16-19.

[17] 张涛,耿壮,刘方超,等.人脐带间充质干细胞对1型糖尿病小鼠皮肤组织AGEs/RAGE/NF-κB信号通路影响的研究[J].中国糖尿病杂志, 2019,27(3):224-228.

[18] BAR Y, RUSS H A, SINTOV E, et al. Redifferentiation of expanded human pancreatic β-cell-derived cells by inhibition of the NOTCH pathway[J]. The Journal of biological chemistry,2012,287(21):17269-17280.

[19] 高峰,刘淑霞,赵玉峰,等.Notch信号通路在糖尿病小鼠肾组织的表达及意义[J].中国组织化学与细胞化学杂志,2014,23(5):445-449.

[20] 王丽娜,方向明,胡建鹏,等.芪地消渴方对2型糖尿病气阴两虚证模型大鼠C-肽、肿瘤坏死因子-α、白细胞介素-6及胰腺组织病理变化的影响[J].安徽中医药大学学报,2017,36(6):72-75.

[21] 赵春霞,王家宁,赵荫涛,等.果糖诱导高血压大鼠血管内皮素-1、内皮素受体-A和内皮源性一氧化氮合酶表达的变化[J].中华高血压杂志, 2005,13(12):788-792.

[22] 苏畅,袁丽,袁嫚嫚,等.雌激素替代治疗影响绝经后女性2型糖尿病患者代谢情况的Meta分析[J].中国糖尿病杂志,2017,25(7):604- 609.

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备注/Memo

基金项目:黑龙江省自然科学基金(H201485);黑龙江中医药大学校级基金面上项目(201838)

更新日期/Last Update:

2020-05-14