[1]魏昭晖,万生芳,舒畅,等.红芪多糖对糖尿病胃轻瘫大鼠小肠组织c-kit、Cx43基因和蛋白表达的影响[J].中国中医药信息杂志,2020,27(8):46-51.[doi:10.3969/j.issn.1005-5304.202001159]
 WEI Zhaohui,WAN Shengfang,SHU Chang,et al.Effects of Hedysarum Polybotrys Polysacchcaide on Expressions of c-kit, Cx43 Gene and Protein in Small Intestine of Diabetic Gastroparesis Rats[J].zhongguo zhongyiyao xinxi zazhi,2020,27(8):46-51.[doi:10.3969/j.issn.1005-5304.202001159]
点击复制

红芪多糖对糖尿病胃轻瘫大鼠小肠组织c-kit、Cx43基因和蛋白表达的影响

参考文献/References:

[1] CHEN Y, XUJ J, LIU S, et al. Electroacupuncture at ST36 ameliorates gastric emptying and rescues networks of interstitial cells of Cajal in the stomach of diabetic rats[J]. PLoS One,2013, 8(12):e83904.

[2] TACK J, CAMILLERI M, CHANG L, et al. Systematic review:cardiovascular safety profile of 5-HT4 agonists developed forgastrointestinal disorders[J]. Alimentary Pharmacology Therapeutics,2012,35(7):745-767.

[3] ZHANG C M, HUANG X, LU H L, et al. Up-regulation of the Ang Ⅱ/AT1 receptor may compensate for the loss of gastric antrum ICC via the PI3k/Akt signaling pathway in STZ-induced diabetic mice[J]. Molecular and Cellular Endocrinology,2016,423:77-86.

[4] HUIZINGA J D, CHEN J H. Interstitial cells of Cajal:update on basic andclinical science[J]. Current Gastroenterology Report, 2014,16:363.

[5] 陈茂鑫,侯敏.黄芪与红芪化学成分及药理作用研究进展与比较[J].中医药导报,2019,25(8):126-128.

[6] 国家药典委员会.中华人民共和国药典:一部[M].北京:中国医药科技出版社,2015:152.

[7] 李厚达.实验动物学[M].北京:中国农业出版社,2003.

[8] 陈奇.中药药理研究方法学[M].北京:人民卫生出版社,2006:31.

[9] 魏昭晖,万生芳,王晓丽.基于“气机升降”理论探析糖尿病胃轻瘫[J].中医研究,2019,32(1):64-65.

[10] HUIZINGA J D, ROBINSON T L, THOMSEN L. The search for the origin of rhythmicity in intestinal contraction;from tissue to single cells[J]. Neurogastroenterology and Motility,2000,12(1):3-9.

[11] THOMSEN L, ROBINSON T L, LEE J C, et al. Interstitial cells of Cajal generate a rhythmic pacemaker current[J]. Nat Med,1998, 4(7):848-851.

[12] 常宗宏,邓尚新,杨娟,等.Cajal间质细胞在胃肠动力障碍性疾病中的研究[J].胃肠病学和肝病学杂志,2019,28(4):387-388.

[13] MARQUEZ-ROSADO L, SOLAN J L, DUNN C A, et al. Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues[J]. Biochimica et Biophysica Acta,2012,1818(8):1985- 1992.

[14] 刘佳丽,陈萌,张冬梅,等.Cx43在调节胃肠运动障碍机制中的研究进展[J].现代生物医学进展,2016,23(16):4577-4579.

[15] SEKI K, KOMURO T. Immunocytochemical demonstration of the gap junction proteins connexin 43 and connexin 45 in the musculature of the rat small intestine[J]. Cell and Tissue Research,2001, 306(3):417-422.

[16] 张花治,金智生,刘莹,等.红芪多糖对糖尿病大鼠视网膜血小板反应蛋白-1和血小板源性生长因子-B表达的影响[J].中国中医药信息杂志, 2017,24(3):38-42.

[17] 王东旭,金智生,张花治,等.红芪多糖对模型小鼠糖尿病心肌病心肌纤维化和基质金属蛋白酶2及其抑制剂表达的影响[J].中国中医药信息杂志,2017,24(4):57-60.

[18] 万生芳,李雅琪,舒畅,等.红芪多糖对GK糖尿病胃轻瘫大鼠胃窦组织MYPT1/p-MYPT1蛋白表达的影响[J].时珍国医国药,2019,30(1):33-36.

[19] 王晓丽,万生芳,魏昭晖,等.红芪多糖对脾虚型糖尿病大鼠Bcl-2/Bax表达的影响[J].时珍国医国药,2019,30(8):1803-1804.

[20] 邵红亮,温娅娜,万生芳,等.红芪多糖对2型糖尿病大鼠血脂代谢紊乱及胰岛素抵抗的影响[J].甘肃科技,2018,34(10):100-101.

相似文献/References:

[1]陈茜,王卫群.益气健脾和胃汤合多潘立酮治疗糖尿病胃轻瘫临床观察[J].中国中医药信息杂志,2008,15(9):77.
 [J].zhongguo zhongyiyao xinxi zazhi,2008,15(8):77.
[2]金智生,李娟娥,张东鹏,等.红芪多糖对改善2型糖尿病模型大鼠胰岛素抵抗的影响[J].中国中医药信息杂志,2007,14(5):27.
 JIN Zhi-sheng,LI Juan-e,ZHANG Dong-peng,et al.Effect of Hedysarum Polybotys Saccharide on Insulin Resisance of Experimental NIDDM Rats[J].zhongguo zhongyiyao xinxi zazhi,2007,14(8):27.
[3]尚红霞,孙蔚明,程卫东,等.红芪多糖对非酒精性脂肪肝大鼠脂代谢及硬脂酰辅酶A去饱和酶1基因表达的影响[J].中国中医药信息杂志,2014,21(7):47.[doi:10.3969/j.issn.1005-5304.2014.07.014]
 SHANG Hong-xia,SUN Wei-ming,CHENG Wei-dong,et al.Effects of Hedysarum Polybotys Saccharide on Lipid Metabolism and Expression of Stearoyl-CoA Desaturase-1 Gene in NAFLD Rats[J].zhongguo zhongyiyao xinxi zazhi,2014,21(8):47.[doi:10.3969/j.issn.1005-5304.2014.07.014]
[4]刘素荣.疏肝健脾法治疗糖尿病胃轻瘫思路探讨[J].中国中医药信息杂志,2004,11(3):227.
[5]张花治,金智生,刘莹,等.红芪多糖对糖尿病大鼠视网膜血小板反应蛋白-1和血小板源性生长因子-B表达的影响[J].中国中医药信息杂志,2017,24(3):38.[doi:10.3969/j.issn.1005-5304.2017.03.010]
 ZHANG Hua-zhi,JIN Zhi-sheng,LIU Ying,et al.Effects of Hedysari Polysaccharide on Expressions of TSP-1 and PDGF-B in Retina of Diabetic Rats[J].zhongguo zhongyiyao xinxi zazhi,2017,24(8):38.[doi:10.3969/j.issn.1005-5304.2017.03.010]
[6]王东旭,金智生,张花治,等.红芪多糖对模型小鼠糖尿病心肌病心肌纤维化和基质金属蛋白酶2及其抑制剂表达的影响[J].中国中医药信息杂志,2017,24(4):57.[doi:10.3969/j.issn.1005-5304.2017.04.015]
 WANG Dong-xv,JIN Zhi-sheng,ZHANG Hua-zhi,et al.Effects of HPS on Myocardial Fibrosis and Expression of MMP-2/TIMP-2 in Model Mice of Diabetic Cardiomyopathy[J].zhongguo zhongyiyao xinxi zazhi,2017,24(8):57.[doi:10.3969/j.issn.1005-5304.2017.04.015]
[7]吴雪芬,刘丽,郑雪娜,等.不同电针刺激强度对糖尿病胃轻瘫大鼠胃肠运动及饥饿素的影响[J].中国中医药信息杂志,2018,25(5):36.[doi:10.3969/j.issn.1005-5304.2018.05.009]
 WU Xue-fen,LIU Li,ZHENG Xue-na,et al.Effects of Different Electroacupuncture Intensity on Gastrointestinal Motility and Ghrelin of Diabetic Gastroparesis Rats[J].zhongguo zhongyiyao xinxi zazhi,2018,25(8):36.[doi:10.3969/j.issn.1005-5304.2018.05.009]
[8]万生芳,李雅琪,王晓丽,等.金芪枳术汤对糖尿病胃轻瘫GK大鼠胃动力的影响[J].中国中医药信息杂志,2018,25(9):56.[doi:10.3969/j.issn.1005-5304.2018.09.014]
 WAN Sheng-fang,LI Ya-qi,WANG Xiao-li,et al.Effects of Jinqi Zhizhu Decoction on Gastric Motility of GK Rats with Diabetic Gastroparesis[J].zhongguo zhongyiyao xinxi zazhi,2018,25(8):56.[doi:10.3969/j.issn.1005-5304.2018.09.014]
[9]张红,李伟,文银萍,等.蚕沙外熨治疗糖尿病胃轻瘫临床研究[J].中国中医药信息杂志,2020,27(7):39.[doi:10.3969/j.issn.1005-5304.202003094]
 ZHANG Hong,LI Wei,WEN Yinping,et al.Clinical Study on Treatment of Diabetic Gastroparesis by Hot Compressing with Silkworm Excrement[J].zhongguo zhongyiyao xinxi zazhi,2020,27(8):39.[doi:10.3969/j.issn.1005-5304.202003094]

备注/Memo

基金项目:国家自然科学基金(81560718);甘肃省中医药管理局科研课题(GZK-2017-3) 通讯作者:万生芳,E-mail:wanshengfang@163.com

更新日期/Last Update:

2020-07-20