[1]苗兰,林力,张颖,等.混合探针法评价天龙通心方对大鼠代谢酶活性的影响[J].中国中医药信息杂志,2020,27(9):51-57.[doi:10.3969/j.issn.1005-5304.202003217]
 MIAO Lan,LIN Li,ZHANG Ying,et al.Evaluation of Effects of Tianlong Tongxin Prescription on Metabolic Enzymes by Mixed Probe in Rats[J].zhongguo zhongyiyao xinxi zazhi,2020,27(9):51-57.[doi:10.3969/j.issn.1005-5304.202003217]
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混合探针法评价天龙通心方对大鼠代谢酶活性的影响

参考文献/References:

[1] 李玲美,付建华,林成仁,等.天龙通心片对心肌缺血再灌注损伤及血液流变学的影响[J].中国实验方剂学杂志,2019,25(10):41-47.

[2] 林力,孙明谦,苗兰,等.中药复方天龙通心在大鼠体内的药代动力学研究[J].药学学报,2017,52(4):575-581.

[3] LEWIS D. Human cytochromes P450 associated with the phase 1 metabolism of drugs and other xenobiotics:A compilation of substrates and inhibitors of the CYP1, CYP2 and CYP3 families[J]. Current Medicinal Chemistry,2003,10(19):1955-1972.

[4] MARTIGNONI M, GROOTHUIS G M, DE KANTER R. Species differences between mouse, rat, dog, monkey and human CYP-mediated drug metabolism, inhibition and induction[J]. Expert Opin Drug Metab Toxicol,2006,2(6):875-894.

[5] OESCH F, FABIAN E, ROBERT L. Xenobiotica-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models[J]. Archives of Toxicology,2018,92:2411-2456.

[6] LO S N, SHEN C C, CHANG C Y, et al. The effect of oxidation on berberine-mediated CYP1 inhibition:oxidation behavior and metabolite-mediated inhibition[J]. Drug Metabolism & Disposition the Biological Fate of Chemicals,2015,43(7):1100.

[7] GUENGERICH F P. Cytochrome P450s and other enzymes in drug metabolism and toxicity[J]. The AAPS Journal,2006,8(1):101-111.

[8] 葛韬.聚氧乙烯脱水山梨醇单油酸酯对大鼠细胞色素P450酶活性及mRNA表达的影响[D].合肥:安徽中医药大学,2018.

[9] ZHANG Y, MIAO L, LIN L, et al. Repeated administration of Sailuotong, a fixed combination of Panax ginseng, Ginkgo biloba, and Crocus sativus extracts for vascular dementia, alters CYP450 activities in rats[J]. Phytomedicine,2018,38:125-134.

[10] FUHR U, DOEHMER J, BATTULA N, et al. Biotransformation of caffeine and theophylline in mammalian cell lines genetically engineered for expression of single cytochrome P450 isoforms[J]. Biochem Pharmacol,1992,43(2):225-235.

[11] LEWIS, DAVID F V. 57 varieties:the human cytochromes P450[J]. Pharmacogenomics,2004,5(3):305-318.

[12] 张颖,苗兰,任常英,等.鸡尾酒探针法评价中药塞络通对大鼠代谢酶的影响[J].中国临床药理学与治疗学,2018,23(9):989-997.

[13] WADANIEL, A HADUCH, M SYREK, et al. Direct and indirect interactions between antidepressant drugs and CYP2C6 in the rat liver during long-term treatment[J]. European Neuropsychopharmacology, 2006,16(8):580-587.

[14] 张瑛瑛.甘草酸二铵对大鼠肝微粒体细胞色素P450酶含量及活性的影响[J].实用药物与临床,2016,3(19):280-282.

[15] ZUBER R, ANZENBACHEROVÁ E, ANZENBACHER P. Cytochromes P450 and experimental models of drug metabolism[J]. J Cell Mol Med,2002, 6(2):189-198.

[16] KOBAYASHI K, URASHIMA K, SHIMADA N, et al. Substrate specificity for rat cytochrome P450 (CYP) isoforms:screening with cDNA-expressed systems of the rat[J]. Biochemical Pharmacology, 2002,63(5):889-896.

[17] 马增春,梁淼,赵佳伟,等.四物汤及其有效成分对大鼠肝脏主要药物代谢酶的影响[J].中国药理学通报,2015,31(9):1319-1323.

[18] 尚芳红,俸珊,陈乾,等.加味佛手散胶囊对大鼠和人肝微粒体 CYP450酶活性的抑制作用[J].药学学报,2016,51(6):926-930.

[19] YE L H, ZHAO X Q, KONG L T, et al. Inhibitory effects of Danhong injection and its major constituents on human cytochrome P450 enzymes\r in vitro[J]. Biomedical Chromatography,2018,32:e4250.

[20] ZHANG J X, QI M J, SHI M Z, et al. Effects of Danhong injection, a traditional Chinese medicine, on nine cytochrome P450 isoforms in vitro[J]. Biomedical Chromatography,2019,33e4454.

[21] QIU F, JIANG J, MA Y, et al. Opposite effects of single-dose and multidose administration of the ethanol extract of Danshen on CYP3A in healthy volunteers[J]. Evidence-Based Complementary and Alternative Medicine,2013,2013:1-8.

[22] QIU F, WANG G, ZHANG R, et al. Effect of Danshen extract on the activity of CYP3A4 in healthy volunteers[J]. British Journal of Clinical Pharmacology,2010,69(6):656-662.

[23] BREIMER D D, SCHELLENS J H. A ‘cocktail’ strategy to assess in vivo oxidative drug metabolism in humans[J]. Trends in Pharmacological Sciences,1990,11(6):223-225.

[24] 赵群,李婕,黄琪,等.门诊处方中氯吡格雷联合用药的调查分析[J]. 中国当代医药,2019,34(26):161-164.

相似文献/References:

[1]董宇,王阶,杨庆,等.CYP450酶与中药代谢相互作用关系研究概况[J].中国中医药信息杂志,2011,18(1):100.[doi:10.3969/j.issn.1005-5304.2011.01.052]
 [J].zhongguo zhongyiyao xinxi zazhi,2011,18(9):100.[doi:10.3969/j.issn.1005-5304.2011.01.052]

备注/Memo

基金项目:国家自然科学基金(81774145、81803770);国家科技重大专项-重大新药创制(2012ZX09103201-049)

更新日期/Last Update:

2020-08-20