[1]王欣波,赵宇,袁星星.安神定志方对阿尔茨海默病大鼠海马组织miR-103a-3p及其介导的Tau蛋白磷酸化的影响[J].中国中医药信息杂志,2021,28(2):62-68.[doi:10.19879/j.cnki.1005-5304.202007309]
 WANG Xinbo,ZHAO Yu,YUAN Xingxing.Effects of Anshen Dingzhi Prescription on miR-103a-3p and Its Mediated Phosphorylation of Tau Protein in Hippocampus of Alzheimer Disease Rats[J].zhongguo zhongyiyao xinxi zazhi,2021,28(2):62-68.[doi:10.19879/j.cnki.1005-5304.202007309]
点击复制

安神定志方对阿尔茨海默病大鼠海马组织miR-103a-3p及其介导的Tau蛋白磷酸化的影响

参考文献/References:

[1] 卢成淑,冯宁,南国,等.石菖蒲及其活性成分防治阿尔茨海默病的研究进展[J].中草药,2016,47(7):1236-1242.

[2] 王昊,赵振宇,沈霞,等.基于系统药理学研究远志治疗阿尔茨海默病的作用机制[J].药学学报,2017,52(10):1554-1561.

[3] 谌勤,罗洪斌,谢文执.板桥党参通过PP2A信号通路改善AD模型大鼠认知功能障碍[J].中国药理学通报,2019,35(9):1232-1239.

[4] 王欣波,赵宇.安神定志方对阿尔茨海默病大鼠Tau蛋白磷酸化及BDNF/TrkB信号通路的影响[J].海南医学院学报,2019,25(21):1612-1616.

[5] WANG Z, XU P, CHEN B, et al. Identifying circRNA-associated- ceRNA networks in the hippocampus of Aβ1-42-induced Alzheimer’s disease-like rats using microarray analysis[J]. Aging (Albany NY),2018,10(4):775-788.

[6] 张云鹤,张一娜,刘歆,等.Aβ1-42诱导原代海马神经细胞建立阿尔茨海默病细胞模型[J].中国老年学杂志,2011,31(11):2027-2029.

[7] PAXINOS G.大鼠脑立体定位图谱[M].3版.诸葛启钏,译.北京:人民卫生出版社,2005:2-30.

[8] 杨婷婷,刘辰庚,王培昌.MicroRNA作为阿尔茨海默病标志物的研究进展[J].中国老年学杂志,2016,36(20):5190-5193.

[9] 杨群,苏波,郑郧,等.阿尔茨海默病小鼠与野生型小鼠海马中miRNA表达差异[J].中国老年学杂志,2016,36(3):532-536.

[10] 徐鑫鑫,林兰,王旭东,等.miR-103a-3p对肺癌A549细胞增殖、迁移和侵袭的影响[J].临床检验杂志,2018,36(8):583-588.

[11] 杨雨澎,杨志,李晓冬.miR-103a-3p通过调控FEZF1/CDC25A途径影响肝癌细胞的增殖和凋亡[J].临床和实验医学杂志,2018,17(11):1158- 1163.

[12] 王敏,杨睿,钟镇宇,等.环状RNA circTCF25通过miR-103a-3p/ miR-107调控CDK6的表达促进膀胱癌的增殖和迁移[J].中国细胞生物学学报,2018,40(6):929-936.

[13] 张亚珍,何贵省,吴晓明,等.miR-103a-3p在乳腺癌组织和血清中的表达及通过下调PDK4抑制乳腺癌细胞的有氧糖酵解及增殖[J].中国肿瘤生物治疗杂志,2018,25(5):490-496.

[14] 贺军,曹金敏,陈国栋,等.miR-103a-3p在胰腺癌细胞中的表达及意义[J].中国医学创新,2015,12(6):1-4.

[15] 林玲,蔡智慧,常全忠.西红花苷对阿尔茨海默病大鼠空间学习记忆的影响[J].中药药理与临床,2016,32(1):75-79.

[16] LASKE C, STELLOS K, HOFFMANN N, et al. Higher BDNF serum levels predict slower cognitive decline in Alzheimer’s disease patients[J]. International Journal of Neuropsychopharmacology, 2011,14(3):399-404.

[17] HOCK C, HEESE K, HULETTE C. Region-specific neurotrophin imbalances in Alzheimer disease:decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas[J]. Archives of Neurology,2000,57(6):846-851.

[18] 许曼玉,许志强.不同形态脑源性神经营养因子与阿尔茨海默病关系研究进展[J].重庆医学,2019,48(6):1025-1028.

[19] 高珊,孔立红.Tau蛋白的过度磷酸化机制及其在阿尔茨海默病中的作用[J].华中科技大学学报(医学版),2016,45(6):711-715.

[20] 王建枝,田青.Tau蛋白过度磷酸化机制及其在阿尔茨海默病神经元变性中的作用[J].生物化学与生物物理进展,2012,39(8):771-777.

相似文献/References:

[1]代 渊,王 飞,徐世军.中医治疗阿尔茨海默病优势述略[J].中国中医药信息杂志,2010,17(8):5.[doi:10.3969/j.issn.1005-5304.2010.08.003]
 [J].zhongguo zhongyiyao xinxi zazhi,2010,17(2):5.[doi:10.3969/j.issn.1005-5304.2010.08.003]
[2]冀俊虎,董联玲,曹娟,等.红景天对阿尔茨海默病大鼠行为学和脑组织抗氧化能力的影响[J].中国中医药信息杂志,2009,16(2):38.
 JI Jun-hu,DONG Lian-ling,CAO Juan,et al.Effects of Integripetal Rhodiola Herb on Ethology and Anti-oxydation Potential of Brain Tissue of Alzheimer’s Disease Model Rats[J].zhongguo zhongyiyao xinxi zazhi,2009,16(2):38.
[3]刘龙涛,李浩.浅谈APP转基因小鼠痴呆模型在中医药领域的应用[J].中国中医药信息杂志,2009,16(9):7.
 [J].zhongguo zhongyiyao xinxi zazhi,2009,16(2):7.
[4]陈玉静,田金洲,王蓉,等.金思维对散发性老年性痴呆模型大鼠学习记忆能力的影响[J].中国中医药信息杂志,2008,15(4):29.
 CHEN Yu-jing,TIAN Jin-zhou,WANG Rong,et al.Effect of GETO on Learning and Memory of Sporadic Alzheimer’s Disease Rats[J].zhongguo zhongyiyao xinxi zazhi,2008,15(2):29.
[5]魏翠柏,贾建平,王芬,等.人参皂苷Rg1、Rb1对淀粉样前体蛋白分泌酶代谢途径的影响[J].中国中医药信息杂志,2008,15(9):28.
 WEI Cui-bai,JIA Jian-ping,WANG Fen,et al.Effect of Ginsenoside Rg1 and Rb1 on Secretase in Metabolic Pathway of Amyloid Precursor Protein[J].zhongguo zhongyiyao xinxi zazhi,2008,15(2):28.
[6]李满生,徐厚谦,金华,等.寿聪胶囊对老年痴呆模型大鼠行为学及过氧化氢酶、单胺氧化酶的影响[J].中国中医药信息杂志,2008,15(10):34.
 LI Man-sheng,XU Hou-qian,JIN Hua,et al.Effect of Shoucong Capsule on Learning-memorial Ability and CAT, MAO Activities in Alzheimer Disease Rats[J].zhongguo zhongyiyao xinxi zazhi,2008,15(2):34.
[7]朱晶,邵水金,崔国红,等.电针血清对β淀粉样蛋白损伤原代培养大鼠海马神经元的保护作用[J].中国中医药信息杂志,2013,20(10):38.[doi:10.3969/j.issn.1005-5304.2013.10.014]
 ZHU Jing,SHAO Shui-jin,CUI Guo-hong,et al.Protective Effects of Electro-acupuncture Serum on β-amyloid Protein Induced Damage of Primarily Cultured Rat Hippcampal Neurons[J].zhongguo zhongyiyao xinxi zazhi,2013,20(2):38.[doi:10.3969/j.issn.1005-5304.2013.10.014]
[8]张松峰,雷蕾,方锐,等.防治阿尔茨海默病药食同源类中药配伍规律研究[J].中国中医药信息杂志,2013,20(11):22.[doi:10.3969/j.issn.1005-5304.2013.11.009]
 ZHANG Song-feng,LEI Lei,FANG Rui,et al.Literature Research of Compatibility Laws of Homologous Chinese Medicine of Medicine and Food in Prevention and Treatment of Alzheimer Disease[J].zhongguo zhongyiyao xinxi zazhi,2013,20(2):22.[doi:10.3969/j.issn.1005-5304.2013.11.009]
[9]刘畅,王梦之,国海东,等.电针对阿尔茨海默病大鼠单核细胞趋化蛋白-1及基质细胞衍生因子-1的影响[J].中国中医药信息杂志,2014,21(5):43.[doi:10.3969/j.issn.1005-5304.2014.05.014]
 LIU Chang,WANG Meng-zhi,GUO Hai-dong,et al.Effects of Electro-acupuncture on Expression of Chemokines MCP-1 and SDF-1 in Alzheimer’s Disease Rats[J].zhongguo zhongyiyao xinxi zazhi,2014,21(2):43.[doi:10.3969/j.issn.1005-5304.2014.05.014]
[10]徐凯,卫东锋,张仰君,等.知母及其提取物改善学习记忆和治疗阿尔茨海默病研究进展[J].中国中医药信息杂志,2014,21(6):132.[doi:10.3969/j.issn.1005-5304.2014.06.046]
 [J].zhongguo zhongyiyao xinxi zazhi,2014,21(2):132.[doi:10.3969/j.issn.1005-5304.2014.06.046]

备注/Memo

基金项目:黑龙江省自然科学基金面上项目(H2018063);黑龙江省中医药科研项目(21102190005)

更新日期/Last Update:

2021-01-25